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Computational Systems Biology

Overview of attention for book
Cover of 'Computational Systems Biology'

Table of Contents

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    Book Overview
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    Chapter 1 DNA Sequencing Data Analysis
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    Chapter 2 Transcriptome Sequencing: RNA-Seq
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    Chapter 3 Capture Hybridization of Long-Range DNA Fragments for High-Throughput Sequencing
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    Chapter 4 The Introduction and Clinical Application of Cell-Free Tumor DNA
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    Chapter 5 Bioinformatics Analysis for Cell-Free Tumor DNA Sequencing Data
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    Chapter 6 An Overview of Genome-Wide Association Studies
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    Chapter 7 Integrative Analysis of Omics Big Data
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    Chapter 8 The Reconstruction and Analysis of Gene Regulatory Networks
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    Chapter 9 Differential Coexpression Network Analysis for Gene Expression Data
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    Chapter 10 iSeq: Web-Based RNA-seq Data Analysis and Visualization
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    Chapter 11 Revisit of Machine Learning Supported Biological and Biomedical Studies
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    Chapter 12 Identifying Interactions Between Long Noncoding RNAs and Diseases Based on Computational Methods
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    Chapter 13 Survey of Computational Approaches for Prediction of DNA-Binding Residues on Protein Surfaces
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    Chapter 14 Computational Prediction of Protein O-GlcNAc Modification
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    Chapter 15 Machine Learning-Based Modeling of Drug Toxicity
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    Chapter 16 Metabolomics: A High-Throughput Platform for Metabolite Profile Exploration
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    Chapter 17 Single-Cell Protein Assays: A Review
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    Chapter 18 Data Analysis in Single-Cell Transcriptome Sequencing
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    Chapter 19 Applications of Single-Cell Sequencing for Multiomics
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    Chapter 20 Progress on Diagnosis of Tuberculous Meningitis
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    Chapter 21 Insights of Acute Lymphoblastic Leukemia with Development of Genomic Investigation
Attention for Chapter 2: Transcriptome Sequencing: RNA-Seq
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Chapter title
Transcriptome Sequencing: RNA-Seq
Chapter number 2
Book title
Computational Systems Biology
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7717-8_2
Pubmed ID
Book ISBNs
978-1-4939-7716-1, 978-1-4939-7717-8
Authors

Zhang, Hong, He, Lin, Cai, Lei, Hong Zhang, Lin He, Lei Cai

Abstract

RNA sequencing (RNA-seq) can not only be used to identify the expression of common or rare transcripts but also in the identification of other abnormal events, such as alternative splicing, novel transcripts, and fusion genes. In principle, RNA-seq can be carried out by almost all of the next-generation sequencing (NGS) platforms, but the libraries of different platforms are not exactly the same; each platform has its own kit to meet the special requirements of the instrument design.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 125 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 15%
Student > Bachelor 19 15%
Student > Master 17 14%
Researcher 13 10%
Student > Doctoral Student 9 7%
Other 11 9%
Unknown 37 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 43 34%
Agricultural and Biological Sciences 18 14%
Medicine and Dentistry 4 3%
Immunology and Microbiology 3 2%
Computer Science 2 2%
Other 13 10%
Unknown 42 34%