Chapter title |
Chromatin immunoprecipitation protocol for Mammalian cells.
|
---|---|
Chapter number | 4 |
Book title |
Transcription Factor Regulatory Networks
|
Published in |
Methods in molecular biology, January 2014
|
DOI | 10.1007/978-1-4939-0805-9_4 |
Pubmed ID | |
Book ISBNs |
978-1-4939-0804-2, 978-1-4939-0805-9
|
Authors |
Makiko Komata, Yuki Katou, Hiroshi Tanaka, Ryuichiro Nakato, Katsuhiko Shirahige, Masashige Bando, Komata, Makiko, Katou, Yuki, Tanaka, Hiroshi, Nakato, Ryuichiro, Shirahige, Katsuhiko, Bando, Masashige |
Abstract |
The genomic approach (ChIP-seq) we introduce here is now a widely used powerful tool to explore protein-DNA interaction at genome-wide level in high resolution. This technology opens up the way to understand how local event mediated by protein-protein or protein-DNA interactions lead to the dynamic changes of overall chromosome structure and how variety of proteins make a regulatory network for the faithful execution of various chromosomal functions (i.e., transcription, replication, recombination, repair, and partition). |
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Mendeley readers
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Unknown | 18 | 90% |
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Researcher | 4 | 20% |
Student > Bachelor | 2 | 10% |
Professor | 2 | 10% |
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Other | 4 | 20% |
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Chemistry | 1 | 5% |
Unspecified | 1 | 5% |
Other | 0 | 0% |
Unknown | 2 | 10% |