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Mendeley readers
Chapter title |
Visualization and Quantitative Measurement of Drug-Induced Platinum Adducts in the Nuclear DNA of Individual Cells by an Immuno-Cytological Assay
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Chapter number | 24 |
Book title |
Urothelial Carcinoma
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Published in |
Methods in molecular biology, January 2018
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DOI | 10.1007/978-1-4939-7234-0_24 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7233-3, 978-1-4939-7234-0
|
Authors |
Margarita Melnikova, Jürgen Thomale, Melnikova, Margarita, Thomale, Jürgen |
Abstract |
Immunocytological staining with adduct-specific antibodies allows the visualization and measurement of structurally defined types of DNA damage in the nuclei of individual cells. Here we describe an immunocytological assay (ICA) procedure for the localization and quantification of such damage, in particular induced by platinum-based anticancer drugs, in cell lines , in primary cell suspensions and in frozen tissue sections. |
Mendeley readers
The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 1 | 20% |
Researcher | 1 | 20% |
Student > Doctoral Student | 1 | 20% |
Student > Master | 1 | 20% |
Unknown | 1 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 2 | 40% |
Agricultural and Biological Sciences | 1 | 20% |
Engineering | 1 | 20% |
Unknown | 1 | 20% |