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Mendeley readers
| Chapter title |
Assessing Cognitive Improvement in People with Down Syndrome: Important Considerations for Drug-Efficacy Trials
|
|---|---|
| Chapter number | 12 |
| Book title |
Cognitive Enhancement
|
| Published in |
Handbook of experimental pharmacology, January 2015
|
| DOI | 10.1007/978-3-319-16522-6_12 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-916521-9, 978-3-31-916522-6
|
| Authors |
Fabian Fernandez, Roger H. Reeves |
| Abstract |
Experimental research over just the past decade has raised the possibility that learning deficits connected to Down syndrome (DS) might be effectively managed by medication. In the current chapter, we touch on some of the work that paved the way for these advances and discuss the challenges associated with translating them. In particular, we highlight sources of phenotypic variability in the DS population that are likely to impact performance assessments. Throughout, suggestions are made on how to detect meaningful changes in cognitive-adaptive function in people with DS during drug treatment. The importance of within-subjects evaluation is emphasized. |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 41 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 22% |
| Researcher | 5 | 12% |
| Student > Ph. D. Student | 4 | 10% |
| Student > Postgraduate | 3 | 7% |
| Student > Doctoral Student | 2 | 5% |
| Other | 4 | 10% |
| Unknown | 14 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 20% |
| Psychology | 4 | 10% |
| Neuroscience | 4 | 10% |
| Nursing and Health Professions | 2 | 5% |
| Agricultural and Biological Sciences | 1 | 2% |
| Other | 4 | 10% |
| Unknown | 18 | 44% |