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Cognitive Enhancement

Overview of attention for book
Attention for Chapter 12: Assessing Cognitive Improvement in People with Down Syndrome: Important Considerations for Drug-Efficacy Trials
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Chapter title
Assessing Cognitive Improvement in People with Down Syndrome: Important Considerations for Drug-Efficacy Trials
Chapter number 12
Book title
Cognitive Enhancement
Published in
Handbook of experimental pharmacology, January 2015
DOI 10.1007/978-3-319-16522-6_12
Pubmed ID
Book ISBNs
978-3-31-916521-9, 978-3-31-916522-6
Authors

Fabian Fernandez, Roger H. Reeves

Abstract

Experimental research over just the past decade has raised the possibility that learning deficits connected to Down syndrome (DS) might be effectively managed by medication. In the current chapter, we touch on some of the work that paved the way for these advances and discuss the challenges associated with translating them. In particular, we highlight sources of phenotypic variability in the DS population that are likely to impact performance assessments. Throughout, suggestions are made on how to detect meaningful changes in cognitive-adaptive function in people with DS during drug treatment. The importance of within-subjects evaluation is emphasized.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 24%
Researcher 5 17%
Student > Postgraduate 3 10%
Student > Ph. D. Student 3 10%
Student > Bachelor 2 7%
Other 3 10%
Unknown 6 21%
Readers by discipline Count As %
Medicine and Dentistry 9 31%
Psychology 3 10%
Neuroscience 2 7%
Nursing and Health Professions 1 3%
Sports and Recreations 1 3%
Other 3 10%
Unknown 10 34%