| Chapter title |
Monitoring Spiking Activity of Many Individual Neurons in Invertebrate Ganglia
|
|---|---|
| Chapter number | 5 |
| Book title |
Membrane Potential Imaging in the Nervous System and Heart
|
| Published in |
Advances in experimental medicine and biology, January 2015
|
| DOI | 10.1007/978-3-319-17641-3_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-917640-6, 978-3-31-917641-3
|
| Authors |
W. N. Frost, C. J. Brandon, A. M. Bruno, M. D. Humphries, C. Moore-Kochlacs, T. J. Sejnowski, J. Wang, E. S. Hill, Frost, W. N., Brandon, C. J., Bruno, A. M., Humphries, M. D., Moore-Kochlacs, C., Sejnowski, T. J., Wang, J., Hill, E. S. |
| Abstract |
Optical recording with fast voltage sensitive dyes makes it possible, in suitable preparations, to simultaneously monitor the action potentials of large numbers of individual neurons. Here we describe methods for doing this, including considerations of different dyes and imaging systems, methods for correlating the optical signals with their source neurons, procedures for getting good signals, and the use of Independent Component Analysis for spike-sorting raw optical data into single neuron traces. These combined tools represent a powerful approach for large-scale recording of neural networks with high temporal and spatial resolution. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 13 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 38% |
| Lecturer | 1 | 8% |
| Student > Doctoral Student | 1 | 8% |
| Student > Master | 1 | 8% |
| Researcher | 1 | 8% |
| Other | 2 | 15% |
| Unknown | 2 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 4 | 31% |
| Biochemistry, Genetics and Molecular Biology | 1 | 8% |
| Linguistics | 1 | 8% |
| Physics and Astronomy | 1 | 8% |
| Agricultural and Biological Sciences | 1 | 8% |
| Other | 2 | 15% |
| Unknown | 3 | 23% |