RT @GaetanBurgio: What an interesting paper that just came out in @natureBiotech from Allan Bradley’s group @tombergk on #CRISPR & on-targe…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @michaelkosicki: We describe extensive Cas9-induced on-target genomic damage. Much of it missed by standard genotyping methods. Publishe…
RT @GaetanBurgio: What an interesting paper that just came out in @natureBiotech from Allan Bradley’s group @tombergk on #CRISPR & on-targe…
RT @GaetanBurgio: What an interesting paper that just came out in @natureBiotech from Allan Bradley’s group @tombergk on #CRISPR & on-targe…
The complexity and ingenuity of #Biology never ceases to fascinate me. How will this affect the #CRISPR hype? First resistance and now extensive genetic mutations! That's why continuous independent research is crucial! @nature @NatureBiotech https://t.c
RT @GaetanBurgio: What an interesting paper that just came out in @natureBiotech from Allan Bradley’s group @tombergk on #CRISPR & on-targe…
RT @GaetanBurgio: What an interesting paper that just came out in @natureBiotech from Allan Bradley’s group @tombergk on #CRISPR & on-targe…
RT @LluisMontoliu: El laboratory de Allan Bradley @sangerinstitute acaba de publicar un estudio en @NatureBiotech en el que nuevamente inci…
What an interesting paper that just came out in @natureBiotech from Allan Bradley’s group @tombergk on #CRISPR & on-target effects aka large deletions, chromosomal insertions after Cas9 double stranded break. Here is my take on this #genetherapy ->
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @LluisMontoliu: A new study from Allan Bradley's lab at @sangerinstitute released today in @NatureBiotech further alerts of the large va…
Tough day for #CRISPR stock space with the recent #Nature #biotech paper detailing extensive on/off target mutagenesis. https://t.co/JmyBhybamB
CRISPR long-range off target effect(?) https://t.co/xu4XroAWBC
RT @CihanTastan_PhD: #CRISPR hisseleri yine çakıldı. $EDIT ↘️5% $CRSP ↘️6% $NTLA ↘️7% #CRISPR /Cas9 gen düzenlemesiyle oluşan genom hasar…
Important read for CRISPER folks https://t.co/2Ldfrfo7jH
On the importance of using multiple independent clones and complementing them for CRISPR editing models: https://t.co/tWPjhOMTlj
RT @LluisMontoliu: A new study from Allan Bradley's lab at @sangerinstitute released today in @NatureBiotech further alerts of the large va…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
#CRISPR hisseleri yine çakıldı. $EDIT ↘️5% $CRSP ↘️6% $NTLA ↘️7% #CRISPR /Cas9 gen düzenlemesiyle oluşan genom hasarının düşünülenden yüksek olduğu tespit edildi. CRISPR ile gen terapilerde daha çok önlem alınması şart #Hucresel_GenetikTerapi https://
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @EricTopol: Questioning the real on-target specificity of #CRISPR genome editing https://t.co/nDT3o0L5pJ @NatureBiotech @sangerinstitut…
In modern times, whenever tech folks hype something up in context of medicine, it has hardly ever turned out, or caused more problems. -EMR ❌ -Data mining any health information ❌ -Replacing physicians with AI ❌ -Fully automated pharmacies ❌ -CRISPR ❌ http
Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/knwIgYTTo7
RT @EricTopol: Questioning the real on-target specificity of #CRISPR genome editing https://t.co/nDT3o0L5pJ @NatureBiotech @sangerinstitut…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
That's why i still don't believe in CRISPR Cas9 potential for Therapeutics. I still believe it should be assessed fully for its merits and demerits before its use in clinics. https://t.co/ERJ39ilS2a
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @Aiims1742: Not the kind of news #CRISPR companies want to hear but there are large & complex ON TARGET deletions & rearrangements due t…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
Ups, not very good (but still very important) news for the future of #CRISPRCas9 gene therapies. I wonder, whether those results hold up for #Cpf1 as well... https://t.co/EApQET7z02
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @Biomaven: This one is more worrying for me than the last scare. https://t.co/cU1r49cAZi
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
A study in Nature Biotechnology has revealed that standard DNA tests miss finding this genetic damage. This has safety implications for future gene therapies using CRISPR/Cas9 https://t.co/2mMCPc2aWn
El laboratory de Allan Bradley @sangerinstitute acaba de publicar un estudio en @NatureBiotech en el que nuevamente incide en los resultados inesperados que todavía produce la técnica #CRISPR en células. De nuevo prudencia. Lo he explicado en este hilo: ht
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
If these findings about #CRISPR hold up (because there will absolutely be scrutiny in this hot field), this could be a major concern for therapeutic applications. But there are many methods that don't require double-stranded breaks w/#CRISPR-Cas9 that are
RT @LluisMontoliu: A new study from Allan Bradley's lab at @sangerinstitute released today in @NatureBiotech further alerts of the large va…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @LluisMontoliu: A new study from Allan Bradley's lab at @sangerinstitute released today in @NatureBiotech further alerts of the large va…
RT @EricTopol: Questioning the real on-target specificity of #CRISPR genome editing https://t.co/nDT3o0L5pJ @NatureBiotech @sangerinstitut…
RT @Aiims1742: Not the kind of news #CRISPR companies want to hear but there are large & complex ON TARGET deletions & rearrangements due t…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @emeKato: https://t.co/XiF9kLLPsC Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangeme…
RT @alixcruse: "genetic consequences observed are not limited to the target locus, as events such as loss-of-heterozygosity will uncover r…
RT @LluisMontoliu: A new study from Allan Bradley's lab at @sangerinstitute released today in @NatureBiotech further alerts of the large va…
RT @MichalBarski: Impressive and very important paper - putting the safety of the current CRISPR/Cas9 technologies into question. https://t…
RT @michaelkosicki: We describe extensive Cas9-induced on-target genomic damage. Much of it missed by standard genotyping methods. Publishe…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @EricTopol: Questioning the real on-target specificity of #CRISPR genome editing https://t.co/nDT3o0L5pJ @NatureBiotech @sangerinstitut…
RT @MichalBarski: Impressive and very important paper - putting the safety of the current CRISPR/Cas9 technologies into question. https://t…
RT @yamagatm3: 「信頼がゆらぐ」のではなくて、皆知っていることで、単に説明できないことや説明しにくいことは、論文にならないので、こういう情報が共有されていないということに過ぎないのでは。実際に実験していない教授や生命倫理学者みたいな人の考えや感覚に頼るのは問題とい…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @yamagatm3: 「信頼がゆらぐ」のではなくて、皆知っていることで、単に説明できないことや説明しにくいことは、論文にならないので、こういう情報が共有されていないということに過ぎないのでは。実際に実験していない教授や生命倫理学者みたいな人の考えや感覚に頼るのは問題とい…
Impressive and very important paper - putting the safety of the current CRISPR/Cas9 technologies into question. https://t.co/TfUGTuhMT4
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @yamagatm3: これが元論文なのだが、こういうのって実際にやっている人なら知っていることだと思う。私も、こういう感じの現象は何度も体験してきている。 https://t.co/B44ClfBTzu https://t.co/iaDw6c7ZBi
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
https://t.co/XiF9kLLPsC Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements 話題の論文はこれか。
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @yamagatm3: これが元論文なのだが、こういうのって実際にやっている人なら知っていることだと思う。私も、こういう感じの現象は何度も体験してきている。 https://t.co/B44ClfBTzu https://t.co/iaDw6c7ZBi
This one is more worrying for me than the last scare. https://t.co/cU1r49cAZi
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @yamagatm3: 「信頼がゆらぐ」のではなくて、皆知っていることで、単に説明できないことや説明しにくいことは、論文にならないので、こういう情報が共有されていないということに過ぎないのでは。実際に実験していない教授や生命倫理学者みたいな人の考えや感覚に頼るのは問題とい…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
"genetic consequences observed are not limited to the target locus, as events such as loss-of-heterozygosity will uncover recessive alleles, whereas translocations, inversions and deletions will elicit long-range transcriptional consequences". Whoa, @Pa
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
Yet another paper from a @nature journal indicates that #CRISPR isn't as specific as we thought. This time, @sangerinstitute scientists showed that CRISPR causes large genome deletions and rearrangements. https://t.co/2oIkO4m6PJ
Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/Llb8sntpXf #genomeediting https://t.co/VE609b0xvS
Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements: https://t.co/afMCUggKOl
RT @yamagatm3: これが元論文なのだが、こういうのって実際にやっている人なら知っていることだと思う。私も、こういう感じの現象は何度も体験してきている。 https://t.co/B44ClfBTzu https://t.co/iaDw6c7ZBi
RT @yamagatm3: 「信頼がゆらぐ」のではなくて、皆知っていることで、単に説明できないことや説明しにくいことは、論文にならないので、こういう情報が共有されていないということに過ぎないのでは。実際に実験していない教授や生命倫理学者みたいな人の考えや感覚に頼るのは問題とい…
Get read for another drop in stocks :/ "Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements" https://t.co/QmIpsIdu2w
RT @yamagatm3: これが元論文なのだが、こういうのって実際にやっている人なら知っていることだと思う。私も、こういう感じの現象は何度も体験してきている。 https://t.co/B44ClfBTzu https://t.co/iaDw6c7ZBi
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @AndyBiotech: #CRISPR stocks getting rocked again... $EDIT -5% $CRSP -6% $NTLA -7% https://t.co/epeGNFxPLI Here is the new @NatureBiote…
RT @yamagatm3: 「信頼がゆらぐ」のではなくて、皆知っていることで、単に説明できないことや説明しにくいことは、論文にならないので、こういう情報が共有されていないということに過ぎないのでは。実際に実験していない教授や生命倫理学者みたいな人の考えや感覚に頼るのは問題とい…
RT @yamagatm3: これが元論文なのだが、こういうのって実際にやっている人なら知っていることだと思う。私も、こういう感じの現象は何度も体験してきている。 https://t.co/B44ClfBTzu https://t.co/iaDw6c7ZBi
Still ongoing debate..on and off targets of CRISP! https://t.co/yrEowTOkkl
「信頼がゆらぐ」のではなくて、皆知っていることで、単に説明できないことや説明しにくいことは、論文にならないので、こういう情報が共有されていないということに過ぎないのでは。実際に実験していない教授や生命倫理学者みたいな人の考えや感覚に頼るのは問題ということの好例。 https://t.co/Favj4kJaPq
A new study from Allan Bradley's lab at @sangerinstitute released today in @NatureBiotech further alerts of the large variety and complexity of repaired alleles (genetic mosaicism) upon in vivo #CRISPR genome editing in mouse and human cells in culture. ht
RT @Aiims1742: Not the kind of news #CRISPR companies want to hear but there are large & complex ON TARGET deletions & rearrangements due t…
RT @yamagatm3: これが元論文なのだが、こういうのって実際にやっている人なら知っていることだと思う。私も、こういう感じの現象は何度も体験してきている。 https://t.co/B44ClfBTzu https://t.co/iaDw6c7ZBi
RT @BiotechRadar: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions & complex rearrangements https://t.co/7uo…