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Stromal Immunology

Overview of attention for book
Attention for Chapter 5: Mesenchymal Stem Cells as Endogenous Regulators of Inflammation
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Chapter title
Mesenchymal Stem Cells as Endogenous Regulators of Inflammation
Chapter number 5
Book title
Stromal Immunology
Published in
Advances in experimental medicine and biology, August 2018
DOI 10.1007/978-3-319-78127-3_5
Pubmed ID
Book ISBNs
978-3-31-978125-9, 978-3-31-978127-3
Authors

Hafsa Munir, Lewis S. C. Ward, Helen M. McGettrick

Abstract

This chapter discusses the regulatory role of endogenous mesenchymal stem cells (MSC) during an inflammatory response. MSC are a heterogeneous population of multipotent cells that normally contribute towards tissue maintenance and repair but have garnered significant scientific interest for their potent immunomodulatory potential. It is through these physicochemical interactions that MSC are able to exert an anti-inflammatory response on neighbouring stromal and haematopoietic cells. However, the impact of the chronic inflammatory environment on MSC function remains to be determined. Understanding the relationship of MSC between resolution of inflammation and autoimmunity will both offer new insights in the use of MSC as a therapeutic, and also their involvement in the pathogenesis of inflammatory disorders.

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 29%
Student > Ph. D. Student 1 14%
Professor > Associate Professor 1 14%
Professor 1 14%
Unknown 2 29%
Readers by discipline Count As %
Medicine and Dentistry 2 29%
Biochemistry, Genetics and Molecular Biology 1 14%
Immunology and Microbiology 1 14%
Chemical Engineering 1 14%
Unknown 2 29%