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Prokaryotic Systems Biology

Overview of attention for book
Cover of 'Prokaryotic Systems Biology'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Metagenomics as a Tool for Enzyme Discovery: Hydrolytic Enzymes from Marine-Related Metagenomes
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    Chapter 2 Investigating Bacterial Protein Synthesis Using Systems Biology Approaches.
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    Chapter 3 Biology and Assembly of the Bacterial Envelope
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    Chapter 4 Comparative Genomics and Evolutionary Modularity of Prokaryotes
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    Chapter 5 Predicting Functional Interactions Among Genes in Prokaryotes by Genomic Context
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    Chapter 6 Functional Implications of Domain Organization Within Prokaryotic Rhomboid Proteases
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    Chapter 7 Mapping Transcription Regulatory Networks with ChIP-seq and RNA-seq.
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    Chapter 8 Quantitative and Systems-Based Approaches for Deciphering Bacterial Membrane Interactome and Gene Function
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    Chapter 9 Prokaryotic Systems Biology
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    Chapter 10 Genetic Interaction Scoring Procedure for Bacterial Species
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    Chapter 11 Mapping the Protein-Protein Interactome Networks Using Yeast Two-Hybrid Screens.
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    Chapter 12 Biogenesis of Escherichia coli DMSO Reductase: A Network of Participants for Protein Folding and Complex Enzyme Maturation.
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    Chapter 13 Microbial Proteome Profiling and Systems Biology: Applications to Mycobacterium tuberculosis
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    Chapter 14 Structural Aspects of Bacterial Outer Membrane Protein Assembly.
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    Chapter 15 Substrate Interaction Networks of the Escherichia coli Chaperones: Trigger Factor, DnaK and GroEL
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    Chapter 16 Genetic, Biochemical, and Structural Analyses of Bacterial Surface Polysaccharides
Attention for Chapter 8: Quantitative and Systems-Based Approaches for Deciphering Bacterial Membrane Interactome and Gene Function
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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Chapter title
Quantitative and Systems-Based Approaches for Deciphering Bacterial Membrane Interactome and Gene Function
Chapter number 8
Book title
Prokaryotic Systems Biology
Published in
Advances in experimental medicine and biology, January 2015
DOI 10.1007/978-3-319-23603-2_8
Pubmed ID
Book ISBNs
978-3-31-923602-5, 978-3-31-923603-2
Authors

Deineko, Viktor, Kumar, Ashwani, Vlasblom, James, Babu, Mohan, Viktor Deineko, Ashwani Kumar, James Vlasblom, Mohan Babu

Abstract

High-throughput genomic and proteomic methods provide a concise description of the molecular constituents of a cell, whereas systems biology strives to understand the way these components function as a whole. Recent developments, such as genome editing technologies and protein epitope-tagging coupled with high-sensitivity mass-spectrometry, allow systemic studies to be performed at an unprecedented scale. Available methods can be successfully applied to various goals, both expanding fundamental knowledge and solving applied problems. In this review, we discuss the present state and future of bacterial cell envelope interactomics, with a specific focus on host-pathogen interactions and drug target discovery. Both experimental and computational methods will be outlined together with examples of their practical implementation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 11%
Unknown 8 89%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 3 33%
Student > Ph. D. Student 2 22%
Researcher 1 11%
Lecturer 1 11%
Unknown 2 22%
Readers by discipline Count As %
Medicine and Dentistry 3 33%
Agricultural and Biological Sciences 1 11%
Chemistry 1 11%
Energy 1 11%
Unknown 3 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2015.
All research outputs
#14,829,358
of 22,834,308 outputs
Outputs from Advances in experimental medicine and biology
#2,265
of 4,951 outputs
Outputs of similar age
#198,089
of 353,198 outputs
Outputs of similar age from Advances in experimental medicine and biology
#100
of 272 outputs
Altmetric has tracked 22,834,308 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,951 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,198 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 272 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.