| Chapter title |
Comparative Genomics and Evolutionary Modularity of Prokaryotes
|
|---|---|
| Chapter number | 4 |
| Book title |
Prokaryotic Systems Biology
|
| Published in |
Advances in experimental medicine and biology, December 2015
|
| DOI | 10.1007/978-3-319-23603-2_4 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-923602-5, 978-3-31-923603-2
|
| Authors |
Cedoljub Bundalovic-Torma, John Parkinson |
| Abstract |
The soaring number of high-quality genomic sequences has ushered in the era of post-genomic research where our understanding of organisms has dramatically shifted towards defining the function of genes within their larger biological contexts. As a result, novel high-throughput experimental technologies are being increasingly employed to uncover physical and functional associations of genes and proteins in complex biological processes. Through the construction and analysis of physical, genetic and metabolic networks generated for the model organisms, such as Escherichia coli, organizational principles of the genome have been deduced, such as modularity, which has important implications toward understanding prokaryotic evolution and adaptation to novel lifestyles. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 8% |
| Unknown | 12 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 3 | 23% |
| Researcher | 3 | 23% |
| Student > Bachelor | 2 | 15% |
| Student > Master | 1 | 8% |
| Professor > Associate Professor | 1 | 8% |
| Other | 1 | 8% |
| Unknown | 2 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 3 | 23% |
| Agricultural and Biological Sciences | 3 | 23% |
| Earth and Planetary Sciences | 2 | 15% |
| Computer Science | 1 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 8% |
| Other | 2 | 15% |
| Unknown | 1 | 8% |