You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Chapter title |
Assessing the Biological Activity of the Glucan Phosphatase Laforin
|
---|---|
Chapter number | 7 |
Book title |
Protein Tyrosine Phosphatases
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3746-2_7 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3744-8, 978-1-4939-3746-2
|
Authors |
Carlos Romá-Mateo, Madushi Raththagala, Mathew S. Gentry, Pascual Sanz, Romá-Mateo, Carlos, Raththagala, Madushi, Gentry, Mathew S., Sanz, Pascual |
Abstract |
Glucan phosphatases are a recently discovered family of enzymes that dephosphorylate either starch or glycogen and are essential for proper starch metabolism in plants and glycogen metabolism in humans. Mutations in the gene encoding the only human glucan phosphatase, laforin, result in the fatal, neurodegenerative, epilepsy known as Lafora disease. Here, we describe phosphatase assays to assess both generic laforin phosphatase activity and laforin's unique glycogen phosphatase activity. |
Mendeley readers
The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 7 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 2 | 29% |
Student > Bachelor | 1 | 14% |
Other | 1 | 14% |
Researcher | 1 | 14% |
Professor > Associate Professor | 1 | 14% |
Other | 0 | 0% |
Unknown | 1 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 57% |
Agricultural and Biological Sciences | 1 | 14% |
Unknown | 2 | 29% |