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Mendeley readers
Chapter title |
Silencing Estrogen Receptor-β with siRNA in Cultured Cells
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Chapter number | 28 |
Book title |
Estrogen Receptors
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Published in |
Methods in molecular biology, January 2016
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DOI | 10.1007/978-1-4939-3127-9_28 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3126-2, 978-1-4939-3127-9
|
Authors |
Ren-Jun Hsu, Jui-Ming Liu, Hsu, Ren-Jun, Liu, Jui-Ming |
Abstract |
Estrogen receptors α and β (ERα and ERβ) are the two genomic estrogen receptors. ERβ was the second of these receptors to be discovered; its structure is similar to that of ERα but they are different in histological distribution. However, the functions of ERα versus ERβ are still unclear. The ability of small interfering RNAs (siRNAs) to silence gene expression has proven to be invaluable for studying gene function in cultured mammalian cells. This chapter describes the use of siRNA to inhibit the expression of ERβ in renal cell carcinoma (RCC) and to further the understanding of ERβ function in RCC. |
Mendeley readers
The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 1 | 50% |
Other | 1 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 1 | 50% |
Unknown | 1 | 50% |