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Chapter title |
Design and Crystallography of Self-Assembling RNA Nanostructures
|
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Chapter number | 9 |
Book title |
RNA Nanostructures
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Published in |
Methods in molecular biology, July 2017
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DOI | 10.1007/978-1-4939-7138-1_9 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7137-4, 978-1-4939-7138-1
|
Authors |
Mark A. Boerneke, Thomas Hermann |
Abstract |
Biological RNA architectures are composed of autonomously folding modules which can be tailored as building blocks for the construction of RNA nanostructures. Designed base pair interactions allow complex nano-objects to self-assemble from simple RNA motifs. X-ray crystallography plays an important role in both the design and analysis of such RNA nanostructures. Here, we describe methods for the design and X-ray crystallographic structure analysis of an RNA square and two different triangles, which self-assemble from short oligonucleotides and serve as a platform for building functional nano-sized nucleic acid architectures. |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 6 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 2 | 33% |
Professor | 1 | 17% |
Other | 1 | 17% |
Student > Master | 1 | 17% |
Researcher | 1 | 17% |
Other | 0 | 0% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 3 | 50% |
Veterinary Science and Veterinary Medicine | 1 | 17% |
Chemistry | 1 | 17% |
Medicine and Dentistry | 1 | 17% |