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Programmed Cell Death

Overview of attention for book
Cover of 'Programmed Cell Death'

Table of Contents

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    Book Overview
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    Chapter 1 Detection of Apoptotic Versus Autophagic Cell Death by Flow Cytometry
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    Chapter 2 In Vivo Apoptosis Imaging Using Site-Specifically 68 Ga-Labeled Annexin V
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    Chapter 3 Detection of Active Caspases During Apoptosis Using Fluorescent Activity-Based Probes
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    Chapter 4 Detection of Initiator Caspase Induced Proximity in Single Cells by Caspase Bimolecular Fluorescence Complementation
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    Chapter 5 In Vitro Use of Peptide Based Substrates and Inhibitors of Apoptotic Caspases
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    Chapter 6 Programmed Cell Death
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    Chapter 7 Analysis of Cell Death Induction in Intestinal Organoids In Vitro
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    Chapter 8 In Vitro Differentiation of Mouse Granulocytes
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    Chapter 9 Programmed Cell Death
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    Chapter 10 Isolation of Cardiomyocytes and Cardiofibroblasts for Ex Vivo Analysis
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    Chapter 11 Programmed Cell Death
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    Chapter 12 Programmed Cell Death
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    Chapter 13 Modeling Metazoan Apoptotic Pathways in Yeast
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    Chapter 14 Characterizing Bcl-2 Family Protein Conformation and Oligomerization Using Cross-Linking and Antibody Gel-Shift in Conjunction with Native PAGE
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    Chapter 15 Using Förster-Resonance Energy Transfer to Measure Protein Interactions Between Bcl-2 Family Proteins on Mitochondrial Membranes
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    Chapter 16 Preparing Samples for Crystallization of Bcl-2 Family Complexes
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    Chapter 17 Programmed Cell Death
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    Chapter 18 Programmed Cell Death
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    Chapter 19 Programmed Cell Death
  21. Altmetric Badge
    Chapter 20 Proteomic Profiling of Cell Death: Stable Isotope Labeling and Mass Spectrometry Analysis
Attention for Chapter 18: Programmed Cell Death
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Chapter title
Programmed Cell Death
Chapter number 18
Book title
Programmed Cell Death
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3581-9_18
Pubmed ID
Book ISBNs
978-1-4939-3579-6, 978-1-4939-3581-9
Authors

Kueh, Andrew J, Herold, Marco J, Kueh, Andrew J., Herold, Marco J., Andrew J. Kueh, Marco J. Herold

Abstract

Clustered, regularly interspaced, short palindromic repeats (CRISPR)/Cas9 technology has been demonstrated to be a useful tool for generating targeted mutations in cell lines and mice. However, the use of CRISPR/Cas9 in a constitutively expressed manner can often result in low targeting efficiencies and lethality due to mutations in essential genes. Here, we describe the use of an inducible lentiviral vector platform, enabling rapid transduction and enrichment of CRISPR/Cas9 positive cells and high levels of targeted mutations upon induction.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 29%
Student > Bachelor 4 19%
Student > Ph. D. Student 3 14%
Student > Master 3 14%
Professor 1 5%
Other 2 10%
Unknown 2 10%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 57%
Agricultural and Biological Sciences 3 14%
Immunology and Microbiology 2 10%
Business, Management and Accounting 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Other 1 5%
Unknown 1 5%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2017.
All research outputs
#20,390,619
of 22,940,083 outputs
Outputs from Methods in molecular biology
#9,915
of 13,127 outputs
Outputs of similar age
#331,233
of 394,075 outputs
Outputs of similar age from Methods in molecular biology
#1,054
of 1,471 outputs
Altmetric has tracked 22,940,083 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,127 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,075 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,471 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.