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RNA Metabolism in Neurodegenerative Diseases

Overview of attention for book
Attention for Chapter 7: Stress Granules and ALS: A Case of Causation or Correlation?
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Chapter title
Stress Granules and ALS: A Case of Causation or Correlation?
Chapter number 7
Book title
RNA Metabolism in Neurodegenerative Diseases
Published in
Advances in neurobiology, January 2018
DOI 10.1007/978-3-319-89689-2_7
Pubmed ID
Book ISBNs
978-3-31-989688-5, 978-3-31-989689-2
Authors

Nikita Fernandes, Nichole Eshleman, J. Ross Buchan, Fernandes, Nikita, Eshleman, Nichole, Buchan, J. Ross

Abstract

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. These aggregates are linked to ALS pathogenesis. Recent evidence has suggested that stress granules may aid the formation of ALS protein aggregates. Here, we summarize current understanding of stress granules, focusing on assembly and clearance. We also assess the evidence linking alterations in stress granule formation and dynamics to ALS protein aggregates and disease pathology.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 30%
Student > Master 9 14%
Researcher 6 9%
Student > Bachelor 6 9%
Student > Doctoral Student 3 5%
Other 10 16%
Unknown 11 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 18 28%
Neuroscience 13 20%
Agricultural and Biological Sciences 7 11%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Medicine and Dentistry 3 5%
Other 6 9%
Unknown 13 20%