| Chapter title |
Therapeutics Against Filovirus Infection
|
|---|---|
| Chapter number | 12 |
| Book title |
Marburg- and Ebolaviruses
|
| Published in |
Current topics in microbiology and immunology, January 2017
|
| DOI | 10.1007/82_2017_12 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-968946-3, 978-3-31-968948-7
|
| Authors |
John Connor, Gary Kobinger, Gene Olinger |
| Abstract |
Therapies for filovirus infections are urgently needed. The paradoxical issue facing therapies is the need for rigorous safety and efficacy testing, adhering to the principle tenant of medicine to do no harm, while responding to the extreme for a treatment option during an outbreak. Supportive care remains a primary goal for infected patients. Years of research into filoviruses has provided possible medical interventions ranging from direct antivirals, host-factor supportive approaches, and passive immunity. As more basic research is directed toward understanding these pathogens and their impact on the host, effective approaches to treat patients during infection will be identified. The ability to manage outbreaks with medical interventions beyond supportive care will require clinical trial design that will balance the benefits of the patient and scientific community. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 13 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 4 | 31% |
| Student > Master | 3 | 23% |
| Student > Doctoral Student | 2 | 15% |
| Researcher | 1 | 8% |
| Professor > Associate Professor | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 2 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 15% |
| Social Sciences | 2 | 15% |
| Agricultural and Biological Sciences | 2 | 15% |
| Medicine and Dentistry | 2 | 15% |
| Nursing and Health Professions | 1 | 8% |
| Other | 1 | 8% |
| Unknown | 3 | 23% |