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Gene Therapy for Neurological Disorders

Overview of attention for book
Cover of 'Gene Therapy for Neurological Disorders'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction to Viral Vectors and Other Delivery Methods for Gene Therapy of the Nervous System
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    Chapter 2 Delivering Transgenic DNA Exceeding the Carrying Capacity of AAV Vectors
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    Chapter 3 Expression of Multiple Functional RNAs or Proteins from One Viral Vector.
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    Chapter 4 Regulated Gene Therapy
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    Chapter 5 Design of shRNA and miRNA for Delivery to the CNS.
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    Chapter 6 Tissue-Specific Promoters in the CNS
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    Chapter 7 Small-Scale Recombinant Adeno-Associated Virus Purification.
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    Chapter 8 Lentivirus Production and Purification
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    Chapter 9 Viral Vector Production: Adenovirus.
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    Chapter 10 Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids
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    Chapter 11 Altering Tropism of rAAV by Directed Evolution
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    Chapter 12 Altering Entry Site Preference of Lentiviral Vectors into Neuronal Cells by Pseudotyping with Envelope Glycoproteins.
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    Chapter 13 Directed Evolution of Adenoviruses
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    Chapter 14 Intraparenchymal Stereotaxic Delivery of rAAV and Special Considerations in Vector Handling
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    Chapter 15 MRI-Guided Delivery of Viral Vectors
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    Chapter 16 Systemic Gene Therapy for Targeting the CNS
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    Chapter 17 Widespread Neuronal Transduction of the Rodent CNS via Neonatal Viral Injection.
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    Chapter 18 AAV-Mediated Gene Transfer to Dorsal Root Ganglion
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    Chapter 19 Gene Therapy of the Peripheral Nervous System: The Enteric Nervous System
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    Chapter 20 Gene Therapy of the Peripheral Nervous System: Celiac Ganglia
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    Chapter 21 Convection Enhanced Delivery of Recombinant Adeno-associated Virus into the Mouse Brain
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    Chapter 22 Nonviral Gene Therapy of the Nervous System: Electroporation
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    Chapter 23 Non-Viral, Lipid-Mediated DNA and mRNA Gene Therapy of the Central Nervous System (CNS): Chemical-Based Transfection
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    Chapter 24 Ex Vivo Gene Therapy Using Human Mesenchymal Stem Cells to Deliver Growth Factors in the Skeletal Muscle of a Familial ALS Rat Model.
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    Chapter 25 Gene Therapy Models of Alzheimer's Disease and Other Dementias.
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    Chapter 26 Viral Vector-Based Modeling of Neurodegenerative Disorders: Parkinson's Disease.
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    Chapter 27 Gene Therapy-Based Modeling of Neurodegenerative Disorders: Huntington's Disease.
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    Chapter 28 Gene Therapy for the Treatment of Neurological Disorders: Amyotrophic Lateral Sclerosis.
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    Chapter 29 Stereotaxic Surgical Targeting of the Nonhuman Primate Caudate and Putamen: Gene Therapy for Huntington's Disease.
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    Chapter 30 Gene Therapy for the Treatment of Neurological Disorders: Metabolic Disorders
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    Chapter 31 Gene Therapy for the Treatment of Neurological Disorders: Central Nervous System Neoplasms
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    Chapter 32 AAV2-Neurturin for Parkinson’s Disease: What Lessons Have We Learned?
Overall attention for this book and its chapters
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Mentioned by

2 news outlets
1 blog
24 tweeters
1 patent


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Gene Therapy for Neurological Disorders
Published by
Springer New York, November 2015
DOI 10.1007/978-1-4939-3271-9
978-1-4939-3270-2, 978-1-4939-3271-9

Manfredsson, Fredric P.

Twitter Demographics

The data shown below were collected from the profiles of 24 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 55 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 20%
Researcher 10 18%
Student > Bachelor 8 15%
Student > Ph. D. Student 6 11%
Student > Postgraduate 4 7%
Other 9 16%
Unknown 7 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 18 33%
Neuroscience 11 20%
Pharmacology, Toxicology and Pharmaceutical Science 6 11%
Agricultural and Biological Sciences 6 11%
Immunology and Microbiology 2 4%
Other 4 7%
Unknown 8 15%