Chapter title |
Citrobacter rodentium Infection Model for the Analysis of Bacterial Pathogenesis and Mucosal Immunology
|
---|---|
Chapter number | 7 |
Book title |
Inflammation and Cancer
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7568-6_7 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7567-9, 978-1-4939-7568-6
|
Authors |
Catherine L. Kennedy, Elizabeth L. Hartland, Kennedy, Catherine L., Hartland, Elizabeth L. |
Abstract |
Citrobacter rodentium is a mouse restricted pathogen that was originally isolated from laboratory mouse colonies and causes transmissible colonic hyperplasia, characterized by thickening of the colon and inflammation. As a natural pathogen of mice, the infection model has proven critical to the development of our understanding of the pathogenesis of enteric disease and the mucosal immune response. In addition to this, some features of disease such as dysbiosis, inflammation, and wound healing replicate features of human inflammatory bowel diseases. As such, the C. rodentium infection model has become a key tool in investigations of many aspects of mucosal immunology. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Australia | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 3 | 30% |
Student > Master | 2 | 20% |
Researcher | 1 | 10% |
Student > Bachelor | 1 | 10% |
Unknown | 3 | 30% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 3 | 30% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 10% |
Veterinary Science and Veterinary Medicine | 1 | 10% |
Nursing and Health Professions | 1 | 10% |
Immunology and Microbiology | 1 | 10% |
Other | 0 | 0% |
Unknown | 3 | 30% |