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Antimicrobial Peptides

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Cover of 'Antimicrobial Peptides'

Table of Contents

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    Book Overview
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    Chapter 1 Antimicrobial Peptides: An Introduction.
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    Chapter 2 Tools for Designing Amphipathic Helical Antimicrobial Peptides
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    Chapter 3 Chemical Synthesis of Antimicrobial Peptides
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    Chapter 4 Microwave-Assisted Synthesis of Antimicrobial Peptides
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    Chapter 5 High-Performance Liquid Chromatography and Mass Spectrometry-Based Design of Proteolytically Stable Antimicrobial Peptides
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    Chapter 6 Determination of Structure and Micellar Interactions of Small Antimicrobial Peptides by Solution-State NMR
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    Chapter 7 Mass Spectrometry Approaches for Determining the Structure of Antimicrobial Peptides
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    Chapter 8 Molecular Dynamics Simulation and Analysis of the Antimicrobial Peptide–Lipid Bilayer Interactions
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    Chapter 9 Calorimetry Methods to Study Membrane Interactions and Perturbations Induced by Antimicrobial Host Defense Peptides
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    Chapter 10 Fluorescence and Absorbance Spectroscopy Methods to Study Membrane Perturbations by Antimicrobial Host Defense Peptides
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    Chapter 11 Applying Fluorescence Correlation Spectroscopy to Investigate Peptide-Induced Membrane Disruption
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    Chapter 12 Macromolecule Biosynthesis Assay and Fluorescence Spectroscopy Methods to Explore Antimicrobial Peptide Mode(s) of Action
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    Chapter 13 Using Confocal Microscopy and Computational Modeling to Investigate the Cell-Penetrating Properties of Antimicrobial Peptides
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    Chapter 14 Atomic Force Microscopy Study of the Interactions of Indolicidin with Model Membranes and DNA
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    Chapter 15 Antimicrobial Peptides
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    Chapter 16 Preparation of Membrane Models of Gram-Negative Bacteria and Their Interaction with Antimicrobial Peptides Studied by CD and NMR
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    Chapter 17 Studying the Interaction of Magainin 2 and Cecropin A with E. coli Bacterial Cells Using Circular Dichroism
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    Chapter 18 Studying the Mechanism of Membrane Permeabilization Induced by Antimicrobial Peptides Using Patch-Clamp Techniques
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    Chapter 19 Assays for Identifying Inducers of the Antimicrobial Peptide LL-37
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    Chapter 20 Methods for Elucidating the Mechanism of Action of Proline-Rich and Other Non-lytic Antimicrobial Peptides
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    Chapter 21 The Interaction of Antimicrobial Peptides with the Membrane and Intracellular Targets of Staphylococcus aureus Investigated by ATP Leakage, DNA-Binding Analysis, and the Expression of a LexA-Controlled Gene, recA
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    Chapter 22 Methods for Investigating Biofilm Inhibition and Degradation by Antimicrobial Peptides
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    Chapter 23 Antimicrobial Peptides
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    Chapter 24 Protocols for Studying Antimicrobial Peptides (AMPs) as Anticancer Agents
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    Chapter 25 Antimicrobial Peptides
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    Chapter 26 Using Disease-Associated Enzymes to Activate Antimicrobial Peptide Prodrugs
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    Chapter 27 Anti-inflammatory Properties of Antimicrobial Peptides and Peptidomimetics: LPS and LTA Neutralization
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    Chapter 28 Protocols for Screening Antimicrobial Peptides That Influence Virulence Gene Expression in Staphylococcus aureus
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    Chapter 29 Methods for In Vitro Analysis of Antimicrobial Activity and Toxicity of Anti-keratitis Peptides: Bacterial Viability in Tears, MTT, and TNF-α Release Assays
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    Chapter 30 Methods for In Vivo/Ex Vivo Analysis of Antimicrobial Peptides in Bacterial Keratitis: siRNA Knockdown, Colony Counts, Myeloperoxidase, Immunostaining, and RT-PCR Assays
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    Chapter 31 Hemolytic Activity of Antimicrobial Peptides
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    Chapter 32 Erratum
Attention for Chapter 25: Antimicrobial Peptides
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Chapter title
Antimicrobial Peptides
Chapter number 25
Book title
Antimicrobial Peptides
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6737-7_25
Pubmed ID
Book ISBNs
978-1-4939-6735-3, 978-1-4939-6737-7
Authors

Arpornsuwan, Teerakul, Sriwai, Wimolpak, Sritanaudomchai, Hathaitip, Roytrakul, Sittiruk, Teerakul Arpornsuwan, Wimolpak Sriwai, Hathaitip Sritanaudomchai, Sittiruk Roytrakul

Abstract

Antimicrobial peptides (AMPs) are of importance in defense mechanism of many organisms and are potential candidate for treatment of infections in animals and humans. AMPs exhibit a wide range of immunomodulatory activities related to innate immunity, wound healing, and inflammation. AMPs also serve as drug delivery vectors, antitumor agents, and mitogenic agents. Here, we describe the investigation of anticancer and cytotoxic activities of antimicrobial peptides by colorimetric MTT assay using smooth muscle, dental pulp stem cell, human colon cancer cell line (SW620), and human oral squamous carcinoma cell line (HSC4).

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 20%
Lecturer 2 13%
Student > Bachelor 1 7%
Professor 1 7%
Student > Master 1 7%
Other 2 13%
Unknown 5 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 27%
Agricultural and Biological Sciences 2 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Immunology and Microbiology 1 7%
Medicine and Dentistry 1 7%
Other 1 7%
Unknown 5 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2016.
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#20,376,559
of 22,925,760 outputs
Outputs from Methods in molecular biology
#9,924
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Outputs of similar age
#355,474
of 420,593 outputs
Outputs of similar age from Methods in molecular biology
#842
of 1,074 outputs
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