| Chapter title |
Unconventional Protein Secretion
|
|---|---|
| Chapter number | 7 |
| Book title |
Unconventional Protein Secretion
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3804-9_7 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3802-5, 978-1-4939-3804-9
|
| Authors |
Amaral, Margarida D, Farinha, Carlos M, Matos, Paulo, Botelho, Hugo M, Margarida D. Amaral, Carlos M. Farinha, Paulo Matos, Hugo M. Botelho |
| Editors |
Andrea Pompa, Francesca De Marchis |
| Abstract |
Secretory traffic became a topical field because many important cell regulators are plasma membrane proteins (transporters, channels, receptors), being thus key targets in biomedicine and drug discovery. Cystic fibrosis (CF), caused by defects in a single gene encoding the CF transmembrane conductance regulator (CFTR), constitutes the most common of rare diseases and certainly a paradigmatic one.Here we focus on five different approaches that allow biochemical and cellular characterization of CFTR from its co-translational insertion into the ER membrane to its delivery to the plasma membrane. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 6% |
| Unknown | 15 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 25% |
| Other | 2 | 13% |
| Student > Master | 2 | 13% |
| Student > Bachelor | 1 | 6% |
| Professor | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 5 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 25% |
| Arts and Humanities | 1 | 6% |
| Agricultural and Biological Sciences | 1 | 6% |
| Computer Science | 1 | 6% |
| Psychology | 1 | 6% |
| Other | 3 | 19% |
| Unknown | 5 | 31% |