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Th9 Cells

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Cover of 'Th9 Cells'

Table of Contents

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    Book Overview
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    Chapter 1 Th9 Cells: New Member of T Helper Cell Family
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    Chapter 2 IL-9: Function, Sources, and Detection
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    Chapter 3 IL-9 Signaling Pathway: An Update
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    Chapter 4 A Method to In Vitro Differentiate Th9 Cells from Mouse Naïve CD4+ T Cells
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    Chapter 5 T Cell Receptor and Co-Stimulatory Signals for Th9 Generation
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    Chapter 6 Polarizing Cytokines for Human Th9 Cell Differentiation
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    Chapter 7 Determining the Frequencies of Th9 Cells from Whole Blood
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    Chapter 8 IL-9 Production by Nonconventional T helper Cells
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    Chapter 9 Prediction and Validation of Transcription Factors Binding Sites in the Il9 Locus
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    Chapter 10 Flow Cytometric Assessment of STAT Molecules in Th9 Cells
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    Chapter 11 Transcription Factors Downstream of IL-4 and TGF-β Signals: Analysis by Quantitative PCR, Western Blot, and Flow Cytometry
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    Chapter 12 Retroviral Transduction and Reporter Assay: Transcription Factor Cooperation in Th9 Cell Development
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    Chapter 13 Transcription Factor Binding Studies in CD4+ T Cells: siRNA Transfection, Chromatin Immunoprecipitation, and Liquid Luminescent DNA Precipitation Assay
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    Chapter 14 Defining Epigenetic Regulation of the Interleukin-9 Gene by Chromatin Immunoprecipitation
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    Chapter 15 Allergic Inflammation and Atopic Disease: Role of Th9 Cells
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    Chapter 16 Characterization of Th9 Cells in the Development of EAE and IBD
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    Chapter 17 B16 Lung Melanoma Model to Study the Role of Th9 Cells in Cancer
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    Chapter 18 Th9 Cells and Parasitic Inflammation: Use of Nippostrongylus and Schistosoma Models
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    Chapter 19 Isolation and Purification of Th9 Cells for the Study of Inflammatory Diseases in Research and Clinical Settings
Attention for Chapter 17: B16 Lung Melanoma Model to Study the Role of Th9 Cells in Cancer
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Chapter title
B16 Lung Melanoma Model to Study the Role of Th9 Cells in Cancer
Chapter number 17
Book title
Th9 Cells
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6877-0_17
Pubmed ID
Book ISBNs
978-1-4939-6876-3, 978-1-4939-6877-0
Authors

Alka Dwivedi, Sushant Kumar, Rahul Purwar

Editors

Ritobrata Goswami

Abstract

T cell therapy has shown remarkable promise in multiple malignancies including melanoma and Acute Lymphoblastic Leukemia (ALL). Recent data demonstrated the differential efficacy of various subsets of T-helper cells in tumor regression. Th9 cells, the new member of T helper cell family, possess superior anti-tumor activity compared to Th1 and Th2 cells in murine model of melanoma. Therefore, it is important to examine the anti-tumor activity of specific subsets of Th cells in tumor models. Here, we describe the methodology of examining the anti-tumor activity of Th9 cells in murine model of melanoma.

Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 67%
Other 1 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 1 33%
Medicine and Dentistry 1 33%
Engineering 1 33%