Chapter title |
Aerosol-Based Cell Therapy for Treatment of Lung Diseases
|
---|---|
Chapter number | 327 |
Book title |
Stem Cell Heterogeneity
|
Published in |
Methods in molecular biology, April 2016
|
DOI | 10.1007/7651_2016_327 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6549-6, 978-1-4939-6550-2
|
Authors |
Egi Kardia, Nur Shuhaidatul Sarmiza Abdul Halim, Badrul Hisham Yahaya, Kardia, Egi, Halim, Nur Shuhaidatul Sarmiza Abdul, Yahaya, Badrul Hisham |
Abstract |
Aerosol-based cell delivery technique via intratracheal is an effective route for delivering transplant cells directly into the lungs. An aerosol device known as the MicroSprayer(®) Aerosolizer is invented to transform liquid into an aerosol form, which then can be applied via intratracheal administration for drug delivery. The device produces a uniform and concentrated distribution of aerosolized liquid. Using the capability of MicroSprayer(®) Aerosolizer to transform liquid into aerosol form, our group has designed a novel method of cell delivery using an aerosol-based technique. We have successfully delivered skin-derived fibroblast cells and airway epithelial cells into the airway of a rabbit with minimum risk of cell loss and have uniformly distributed the cells into the airway. This chapter illustrates the application of aerosol device to deliver any type of cells for future treatment of lung diseases. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 37% |
Student > Ph. D. Student | 4 | 21% |
Student > Bachelor | 2 | 11% |
Professor > Associate Professor | 2 | 11% |
Unknown | 4 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 5 | 26% |
Medicine and Dentistry | 2 | 11% |
Nursing and Health Professions | 1 | 5% |
Chemical Engineering | 1 | 5% |
Agricultural and Biological Sciences | 1 | 5% |
Other | 1 | 5% |
Unknown | 8 | 42% |