↓ Skip to main content

Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations

Overview of attention for book
Attention for Chapter 1: Evolution of Immunity and Pathogens.
Altmetric Badge

Mentioned by

twitter
1 tweeter

Readers on

mendeley
18 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Evolution of Immunity and Pathogens.
Chapter number 1
Book title
Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
Published in
Results and problems in cell differentiation, January 2015
DOI 10.1007/978-3-319-20819-0_1
Pubmed ID
Book ISBNs
978-3-31-920818-3, 978-3-31-920819-0
Authors

Jack, Robert S, Robert S. Jack

Abstract

Host and pathogen engage in a constant evolutionary struggle known as a "Red Queen Paradigm". In this struggle, natural selection favours the pathogen which evolves effective virulence mechanisms and the host which is able to field adequate resistance strategies. A number of factors limit what each side can do. These include the fact that the elaboration of virulence or resistance mechanisms results in costs in genetic fitness and requires the use of ever more of the limited number of genes available in the genome. In addition, since the pathogen usually has a very much shorter generation time than the host, it can fix new virulence mutations much more quickly than the host can evolve matching resistance mechanisms. Finally, the host must ensure that its defence system does not result in unacceptable levels of collateral damage to its own tissues. This chapter briefly outlines how these considerations shape host-pathogen interactions.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 22%
Student > Master 4 22%
Professor 3 17%
Student > Postgraduate 2 11%
Researcher 2 11%
Other 2 11%
Unknown 1 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 50%
Biochemistry, Genetics and Molecular Biology 2 11%
Mathematics 2 11%
Immunology and Microbiology 2 11%
Medicine and Dentistry 1 6%
Other 0 0%
Unknown 2 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2016.
All research outputs
#6,544,960
of 7,556,298 outputs
Outputs from Results and problems in cell differentiation
#70
of 99 outputs
Outputs of similar age
#200,821
of 241,859 outputs
Outputs of similar age from Results and problems in cell differentiation
#2
of 2 outputs
Altmetric has tracked 7,556,298 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 99 research outputs from this source. They receive a mean Attention Score of 1.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,859 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.