↓ Skip to main content

MicroRNA Profiling

Overview of attention for book
Cover of 'MicroRNA Profiling'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 MiRNA Biogenesis and Regulation of Diseases: An Overview.
  3. Altmetric Badge
    Chapter 2 Assessment of Basic Biological Functions Exerted by miRNAs.
  4. Altmetric Badge
    Chapter 3 Extraction of miRNAs from Formalin-Fixed Paraffin-Embedded (FFPE) Tissues.
  5. Altmetric Badge
    Chapter 4 MicroRNA Profiling
  6. Altmetric Badge
    Chapter 5 MicroRNA Profiling of Exosomes.
  7. Altmetric Badge
    Chapter 6 MiRNA Profiling in Human Induced Pluripotent Stem Cells.
  8. Altmetric Badge
    Chapter 7 MiRNA Expression in Cystic Fibrosis Bronchial Epithelial Cells.
  9. Altmetric Badge
    Chapter 8 TaqMan Low Density Array: MicroRNA Profiling for Biomarker and Oncosuppressor Discovery.
  10. Altmetric Badge
    Chapter 9 Detection of MicroRNAs in Brain Slices Using In Situ Hybridization.
  11. Altmetric Badge
    Chapter 10 Exosomal MicroRNA Discovery in Age-Related Macular Degeneration.
  12. Altmetric Badge
    Chapter 11 Profiling the MicroRNA Payload of Exosomes Derived from Ex Vivo Primary Colorectal Fibroblasts.
  13. Altmetric Badge
    Chapter 12 Circulating MicroRNAs in Cancer.
  14. Altmetric Badge
    Chapter 13 Profiling Circulating miRNAs from the Plasma of Individuals with Metabolic Syndrome.
  15. Altmetric Badge
    Chapter 14 Manipulating MiRNA Expression to Uncover Hidden Functions.
  16. Altmetric Badge
    Chapter 15 Analysis of the Distribution Profiles of Circulating MicroRNAs by Asymmetrical Flow Field Flow Fractionation.
  17. Altmetric Badge
    Chapter 16 MicroRNA Expression Profiling Using Agilent One-Color Microarray.
  18. Altmetric Badge
    Chapter 17 A Multiplex Ligation Assay for miRNA Copy Number Profiling.
  19. Altmetric Badge
    Chapter 18 Practical Bioinformatics Analysis of MiRNA Data Using Online Tools.
  20. Altmetric Badge
    Chapter 19 Visualization and Analysis of MiRNA-Targets Interactions Networks.
  21. Altmetric Badge
    Chapter 20 Guidelines on Designing MicroRNA Sponges: From Construction to Stable Cell Line.
  22. Altmetric Badge
    Chapter 21 Customization of Artificial MicroRNA Design.
Attention for Chapter 19: Visualization and Analysis of MiRNA-Targets Interactions Networks.
Altmetric Badge

Citations

dimensions_citation
4 Dimensions

Readers on

mendeley
21 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Visualization and Analysis of MiRNA-Targets Interactions Networks.
Chapter number 19
Book title
MicroRNA Profiling
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6524-3_19
Pubmed ID
Book ISBNs
978-1-4939-6522-9, 978-1-4939-6524-3
Authors

Luis E. León, Sebastián D. Calligaris

Editors

Sweta Rani

Abstract

MicroRNAs are a class of small, noncoding RNA molecules of 21-25 nucleotides in length that regulate the gene expression by base-pairing with the target mRNAs, mainly leading to down-regulation or repression of the target genes. MicroRNAs are involved in diverse regulatory pathways in normal and pathological conditions. In this context, it is highly important to identify the targets of specific microRNA in order to understand the mechanism of its regulation and consequently its involvement in disease. However, the microRNA target identification is experimentally laborious and time-consuming. The in silico prediction of microRNA targets is an extremely useful approach because you can identify potential mRNA targets, reduce the number of possibilities and then, validate a few microRNA-mRNA interactions in an in vitro experimental model. In this chapter, we describe, in a simple way, bioinformatics guidelines to use miRWalk database and Cytoscape software for analyzing microRNA-mRNA interactions through their visualization as a network.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 24%
Student > Master 3 14%
Student > Ph. D. Student 3 14%
Student > Bachelor 1 5%
Student > Doctoral Student 1 5%
Other 3 14%
Unknown 5 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 38%
Biochemistry, Genetics and Molecular Biology 5 24%
Environmental Science 1 5%
Decision Sciences 1 5%
Neuroscience 1 5%
Other 1 5%
Unknown 4 19%