RT @plantsciences: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/b…
RT @plantsciences: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/b…
RT @plantsciences: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/b…
Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/b4zNh49thB
@zinkant @SZ "The observed genomic damage in mitotically active cells caused by CRISPR–Cas9 editing may have pathogenic consequences." https://t.co/5OeVbE3ibh
unwanted side effects of #crispr gene editing? Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/LjDUYW6oYU
Also reading: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/pN4gFbkSQf
RT @NCIgenomics: #CRISPR/Cas9 may lead to large deletions and complex rearrangements in cells with working DNA repair machinery https://t.c…
@carlzimmer Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/xwTw4mdJwl EAT GMOs, anyway.
I joke: For real, or will this just let someone sneak in some good human-enhancement stuff? (Whoops, Mrs. Smith, we've accidentally generated a high risk of prodigious mathematical ability in your child...) #CRISPR https://t.co/UHK0I9mj14
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
@KURIERat leider nicht ganz ohne Nebenwirkungen https://t.co/EwhhDc7AFG
CRISPR induces genome instability and creates deletions and rearrangements: https://t.co/tIRaiDJpox
@annevkessel @NEMOkennislink Allan Bradley van het Wellcome Sanger Institute vertelde dit in interview. In onderzoek bleek 20% van alle cellen deleties of herschikkingen van meer dan honderd(en) DNA strengen, die daardoor kankercellen kunnen worden. Het re
@BenjaminBidder @SPIEGELONLINE Das ist kein Kommentar, sondern die Propaganda der Gentech-Industrie. Bei deren Studien werden solche Fakten verschwiegen, oder? https://t.co/rLKeg2OoRc (Dank an @KlausRiede )
Sleeping pitfalls in CRISPR-Cas9 technology? #CRISPR #Cas9 #genetherapy https://t.co/CvgpkljSKm
RT @OrenoReSource: ゲノム編集でDNA消失、新技術の信頼ゆらぐ 英チーム:朝日新聞 https://t.co/oCvQSI5stf
@Hiddemhigh Benieuwd ook met welke argumenten u dit onderzoek naar de prullenmand verwijst: https://t.co/fzLHCXg6VJ
ゲノム編集でDNA消失、新技術の信頼ゆらぐ 英チーム:朝日新聞 https://t.co/oCvQSI5stf
@sci_tweets_ #CRISPR wurde doch nicht #verboten . Und das niemand hundertprozentig weiss was noch passiert zeigt doch diese Arbeit https://t.co/kSO03Twkzc
First systematic assessment of unexpected events resulting from CRISPR/Cas9 editing in therapeutically relevant cells: changes in the DNA have been seriously underestimated https://t.co/9QbMghFRHz
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
oje, wo soll man da anfangen? Verbraucher als Deppen hinstellen, die #keineAhnung haben (siehe CNP), nur wissenschaftliche Arbeiten kommentieren, die ins Konzept passen, aber nicht diese https://t.co/kSO03Twkzc (und das ist nur #gentechnik #CRISPR).. https
Why that noise about #ECJ ruling? #CRISPR actually is not as #safe as science thought. See e.g. news in this thread: https://t.co/yzTfKoxHIo Also interesting: The "rebound effect' for #food". https://t.co/FwnEIEgRaR #future #agritech #GMOs #GMO
@Jluise2 hier noch ein neues @nature paper, das m.E. zeigt, dass die #CRISPR Methode noch nicht ganz beherrscht wird:" DNA breaks introduced by single-guide RNA/Cas9 frequently resolved into deletions extending over many kilobases" https://t.co/kSO03Twkzc
and maybe there are good reasons https://t.co/kSO03Twkzc show that " DNA breaks introduced by single-guide RNA/Cas9 frequently resolved into deletions extending over many kilobases" https://t.co/mvmJiXkX17
@ForscherRobert findet man irgendwo eigentlich die vollständige Urteilsbegründung? Und was meinen die #Pflanzenforscher zu diesem #CRISPR Artikel in @nature ? https://t.co/kSO03Twkzc
@worklifesthg verstehe ich nicht, die #TEchnik wurde doch nicht #verboten! Und #immerhin ist die Entdeckerin der Methode Direktorin eines MPI. Im übrigen ist alles nicht ganz so einfach, siehe https://t.co/kSO03Twkzc
@dw_wissenschaft hoffentlich kennt der Autor auch die neueste Literatur https://t.co/kSO03Twkzc authors "show that DNA breaks introduced by single-guide RNA/Cas9 frequently resolved into deletions extending over many kilobases" #liestnurkeiner
@sambarix genau! Wie immer gilt: #Lesenbildet https://t.co/kSO03Twkzc Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements #journalclub
gute #Infografik! Jetzt kann sich jeder selber fragen und recherchieren: wie findet die #Genschere den Leitfaden? Wie zuverlässig? Und wenn der Leitfaden an anderen Stellen des riesigen Pflanzengenoms nochmal vorkommt, was dann? Mehr dazu hier https://t.co
@johan_emmens @GreenpeaceNL @volkskrant Die gerichtheid valt best mee: https://t.co/VQ8JGbezBY Wij zijn zeker niet tegen onderzoek, maar gegeven onbekendheid risico's en recht transparantie voor consumenten zijn we blij met het oordeel van het Hof. Het is
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @nresearchnews: CRISPR–Cas9 genome editing can cause deletions and rearrangements near the target site. This finding suggests that resea…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
CRISPR–Cas9 genome editing can cause deletions and rearrangements near the target site. This finding suggests that researchers overseeing CRISPR–Cas9-based human therapies must closely monitor sequence changes in genome-edited cells https://t.co/6LZPrOVrDl
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
@NCad_Nederland Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements Published: 16 July 2018 https://t.co/KCnRffRklv
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @nicoladituri: La tecnica #CRISPR per modificare il DNA può vandalizzare i geni dell'uomo. Su @nature lo studio che dimostra come grandi…
...this doesn't sound good for $CRSP https://t.co/YNlB1gqHq9
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
Might the promise of CRISPR be ignoring potentially dramatic genotoxic consequences? https://t.co/bvFIEo6QOF
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @garyruskin: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements. Via @NatureBiot…
RT @michaelkosicki: We describe extensive Cas9-induced on-target genomic damage. Much of it missed by standard genotyping methods. Publishe…
RT @KJegalian: I could follow #genomeeditconf today or I could forgo the angst, trusting in biology's complications. https://t.co/UfpGEDIKRa
Wellcome Sanger scientists: Repair of CRISPR-Cas9-induced dsDNA breaks leads to large deletions & complex rearrangements: damage was underestimated. Is editing the human germline really morally permissible with this level of collateral damage? #CRISPR
I could follow #genomeeditconf today or I could forgo the angst, trusting in biology's complications.
Everything linked to the "father of gene therapy" has since been linked to pathology via "Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements" https://t.co/Q8Rr58Drph reported as: https://t.co/Oq4dCfS9G
Is #CRISPR doing more harm than good? Discuss - here - an overview of some of the pitfalls https://t.co/NIERhZP3tM as reported in .@NatureBiotech https://t.co/we431OpmvF
RT @NCIgenomics: #CRISPR/Cas9 may lead to large deletions and complex rearrangements in cells with working DNA repair machinery https://t.c…
RT @samstudio8: well it's like my mum always said, you shouldn't run around with scissors https://t.co/qFUbaQBDEM
"Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements" https://t.co/8BVOuRJwAl
Looks as if indeed nothing is perfect, not even #CRISPR "The observed genomic damage in mitotically active cells caused by CRISPR–Cas9 editing may have pathogenic consequences." Overview: https://t.co/xRBclMv0wL Full paper: https://t.co/OR8SMJDCkc http
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
https://t.co/iJWFTe7h7z Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
RT @garyruskin: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements. Via @NatureBiot…
RT @NCIgenomics: #CRISPR/Cas9 may lead to large deletions and complex rearrangements in cells with working DNA repair machinery https://t.c…
RT @NCIgenomics: #CRISPR/Cas9 may lead to large deletions and complex rearrangements in cells with working DNA repair machinery https://t.c…
RT @NCIgenomics: #CRISPR/Cas9 may lead to large deletions and complex rearrangements in cells with working DNA repair machinery https://t.c…
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
#CRISPR/Cas9 may lead to large deletions and complex rearrangements in cells with working DNA repair machinery https://t.co/bJGOgnzY9Z https://t.co/yMbno2DpHN
Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements. Via @NatureBiotech https://t.co/c0Ze1u2ZWI
New story about off-target effects by CRISPR out on nature biotech! Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements Michael Kosicki, Kärt Tomberg & Allan Bradley h
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
Long-reads to the rescue???...! "Clustering of PacBio reads yielded 183 unique, edited, high-quality alleles derived from three different gRNAs. These alleles ranged from simple deletions and insertions to complex rearrangements." https://t.co/vsKmU66szq
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @seirinji: クリスパー(遺伝子改変技法 ) 意図せぬ遺伝子損傷を引き起こしていたか。 ※論文は英文で書かれています(掲載先Nature) ※ログインが必要な場合があります (クリスパー•遺伝子改変技法について ) https://t.co/tCKH3o4l…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @NatureBiotech: Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/…
RT @ensembl: How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of man…
Still a long way to go...
RT @ZymoResearch: RT @NatureBiotech "Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangem…
La tecnica #CRISPR per modificare il DNA può vandalizzare i geni dell'uomo. Su @nature lo studio che dimostra come grandi blocchi di DNA vengono eliminati e invertiti. "Probabile" lo sviluppo di cellule tumorali, secondo gli scienziati https://t.co/T0bM6XD
Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements https://t.co/urRfd6hGdh
How specific is #GeneEditing using #CRISPR? New @NatureBiotech study shows repair of DNA breaks can result in deletions of many kb & complex rearrangements! https://t.co/gIvztVwb0F https://t.co/HPDgZxeVAs
There are some unintended consequences of #CRISPR gene editing after all?! https://t.co/OxkRuBMv7l https://t.co/Ze4UEfvcRJ
RT @tuuliel: We've seen the exact same thing in my lab, and it's a huge headache. Great to have this properly documented and published. Con…
RT @NatureBiotech "Repair of double-strand breaks induced by #CRISPR–Cas9 leads to large deletions and complex rearrangements #genomeeditingpic.twitter.com/VE609b0xvS" https://t.co/C0psqSYwjo
クリスパー(遺伝子改変技法 ) 意図せぬ遺伝子損傷を引き起こしていたか。 ※論文は英文で書かれています(掲載先Nature) ※ログインが必要な場合があります (クリスパー•遺伝子改変技法について ) https://t.co/tCKH3o4llf https://t.co/ddBixFh6ig