Chapter title |
Peptide Vaccine Against Paracoccidioidomycosis
|
---|---|
Chapter number | 9 |
Book title |
Vaccines for Invasive Fungal Infections
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7104-6_9 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7103-9, 978-1-4939-7104-6
|
Authors |
Carlos P. Taborda, Luiz R. Travassos, Taborda, Carlos P., Travassos, Luiz R. |
Editors |
Markus Kalkum, Margarita Semis |
Abstract |
The chapter reviews methods utilized for the isolation and characterization of a promising immunogen candidate, aiming at a human vaccine against paracoccidioidomycosis. Peptide P10 carries a T-CD4+ epitope and was identified as an internal sequence of the major diagnostic antigen known as gp43 glycoprotein. It successfully treated massive intratracheal infections by virulent Paracoccidioides brasiliensis in combination with chemotherapy.An introduction about the systemic mycosis was found essential to understand the various options that were considered to design prophylactic and therapeutic vaccine protocols using peptide P10. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 3 | 19% |
Student > Master | 2 | 13% |
Student > Doctoral Student | 1 | 6% |
Other | 1 | 6% |
Student > Ph. D. Student | 1 | 6% |
Other | 3 | 19% |
Unknown | 5 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 7 | 44% |
Medicine and Dentistry | 2 | 13% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Engineering | 1 | 6% |
Unknown | 5 | 31% |